GPU Lane Sharing is the rerouting of PCIe lanes between the CPU to the GPU on the motherboard. The PCIe lanes available to your graphics card slot, drop from x16 to x8, the motherboard reroutes 8 lanes to other slots - typically fast Gen5 M.2 slots or additional Gen5 PCIe expansion slots.
Think of it as the only way to get more connectivity directly from the CPU with the fastest lanes. Because it increases the cost of the board, determining whether you want/need it is key.
The term "GPU Lane Sharing" was coined by the PC community, and it often carries a negative connotation. Gamers hear "your GPU drops to x8" and immediately assume something is wrong. But here's what most people don't realize: this is an intentional design choice that enables more Gen5 connectivity on your motherboard.